期刊论文详细信息
BMC Musculoskeletal Disorders
The comparison of dexamethasone and triamcinolone periarticular administration in total knee arthroplasty: retrospective cohort study
Hirotaka Chikuda1  Shogo Hashimoto1  Masanori Terauchi2  Kazuhisa Hatayama2  Atsufumi Oshima3  Hibiki Kakiage3 
[1] Department of Orthopaedic Surgery, Gunma University Graduate School of Medicine, 3-39-15 Showa-machi, 371-8511, Maebashi, Gunma, Japan;Department of Orthopaedic Surgery, Japan Community Health Care Organization Gunma Central Hospital, 1-7-13 Koun-cho, 371-0025, Maebashi, Gunma, Japan;Department of Orthopaedic Surgery, Japan Community Health Care Organization Gunma Central Hospital, 1-7-13 Koun-cho, 371-0025, Maebashi, Gunma, Japan;Department of Orthopaedic Surgery, Gunma University Graduate School of Medicine, 3-39-15 Showa-machi, 371-8511, Maebashi, Gunma, Japan;
关键词: Total knee arthroplasty;    Periarticular injection;    Corticosteroid;    Dexamethasone;    Triamcinolone acetonide;   
DOI  :  10.1186/s12891-022-05048-8
来源: Springer
PDF
【 摘 要 】

BackgroundIntraoperative periarticular injection of corticosteroid effectively reduces perioperative pain in total knee arthroplasty (TKA). However, which corticosteroid is most effective for intraoperative periarticular injection remains controversial. We compared the effects of corticosteroids between dexamethasone and triamcinolone acetonide periarticular administration for reducing pain and postoperative nausea and increasing fasting blood glucose concentrations during the perioperative period following TKA.MethodsOne hundred and two patients who underwent TKA from August 2018 to September 2020 were divided into two groups: one received 10 mg dexamethasone for intraoperative periarticular injection and another receiving 40 mg triamcinolone acetonide. Postoperative pain scores at rest and during walking and nausea scores were recorded using a 0-to-10 Numerical Rating Scale. C-reactive protein (CRP) and fasting blood glucose levels were measured pre- and postoperatively.ResultsPain scores in the triamcinolone group were significantly lower than in the dexamethasone group at rest 7 days postoperatively (1.5 vs. 2.0; p = 0.046) and while walking at both 72 h (3.9 vs. 4.8; p = 0.008) and 7 days postoperatively (3.2 vs. 4.0; p = 0.03). The CRP levels in the triamcinolone group were significantly lower than in the dexamethasone group at 7 days postoperatively (1.6 mg/dl vs. 3.0 mg/dl: p < 0.001). The fasting blood glucose levels at 1 day postoperatively were increased in both groups but not significantly different between the groups. No significant differences in the nausea score were noted between the groups.ConclusionsTriamcinolone acetonide periarticular administration provided greater pain relief by reducing inflammation to a greater degree than dexamethasone.

【 授权许可】

CC BY   

【 预 览 】
附件列表
Files Size Format View
RO202202174395609ZK.pdf 1442KB PDF download
  文献评价指标  
  下载次数:9次 浏览次数:0次