Effects of high-intensity interval training on improving arterial stiffness in Chinese female university students with normal weight obese: a pilot randomized controlled trial

Journal of Translational Medicine

Jingyun Hu¹  Leichao Liang²  Yuanyuan Yang²  Shihao Jia²  Ruoyu Yang²  Qianle Liu²  Liyan Wang²  Ruiyi Chen²  Yu Ren²  Min Liu³  Lei Zhu³  Ming Cai⁴ 

[1] Central Lab, Shanghai Pudong New Area People’s Hospital, 490 Chuanhuan South Road, 201299, Shanghai, China;College of Rehabilitation Science, Shanghai University of Medicine & Health Sciences, 257 Tianxiong Road, 201318, Shanghai, China;College of Sport Sciences, Qufu Normal University, 273165, Qufu, Shandong Province, China;Shanghai University of Medicine & Health Sciences Affiliated Zhoupu Hospital, 1500 Zhouyuan Road, 201318, Shanghai, China;

关键词: High-intensity interval training;    Normal weight obese;    Female university students;    Arterial stiffness;    Body composition;   

DOI  :  10.1186/s12967-022-03250-9

来源: Springer

【 摘 要 】

BackgroundHigh intensity interval training (HIIT) has been reported to exert better effects on cardiovascular fitness in obesity, but little known about the arterial stiffness (AS) in female university students with normal weight obesity (NWO). Thus, this study aimed to investigate the effects of HIIT on the body composition, heart rate (HR), blood pressure (BP), blood lipids metabolism as well as the novel parameters of propensity for AS (arterial velocity pulse index [AVI], arterial pressure volume index [API]) for female university students with NWO.MethodsForty female university students with NWO were randomly assigned to control group (n = 20) and HIIT group (3 bouts of 9‑min intervals at 90% of the maximal heart rate [HRmax], interspersed by 1 min rest, 5 days a week, n = 20). Tests were performed before and after 4 weeks of training. Repeated measures ANOVA and simple effect test analysis were used to analyze dependent variable changes.ResultsAfter 4 weeks HIIT statistically significantly improved the body composition by decreasing the body mass index, body fat percent, total body fat mass (BFM), BFM of left arm, measured circumference of left arm, and obesity degree, and increasing the total body skeletal muscle mass, protein content, total body water, fat free mass, body cell mas, and InBody score. HIIT also statistically significantly decreased the HR and BP. As for the lipid profile, HIIT obviously ameliorated the blood lipids metabolism by decreasing the levels of total cholesterol (TC), triglyceride, low-density lipoprotein, and TC/HDL, and increasing the levels of high-density lipoprotein (HDL). In addition, the AVI and API were markedly decreased via HIIT intervention.ConclusionsHIIT produced significant and meaningful benefits for body composition, HR, BP, and blood lipids metabolism, and could decrease AS in female university students with NWO. This suggests that HIIT may effectively reduce the risk of arteriosclerosis and protect the cardiovascular function for female university students with NWO.Trial registration ChiCTR2100050711. Registered 3 September 2021. Retrospectively registered.

【 授权许可】

CC BY