DNA methylation signatures in Blood DNA of Hutchinson–Gilford Progeria syndrome

Aging Cell

Nady El Hajj¹  Yosra Bejaoui¹  Aleem Razzaq¹  Abeer Qannan¹  Henning F. Horn¹  Tanvir Alam²  Steve Horvath³  Andre Megarbane⁴  George M. Martin⁵  Junko Oshima⁶  Noha A. Yousri⁷  Ramya Potabattula⁸  Thomas Haaf⁸ 

[1] College of Health and Life Sciences, Qatar Foundation, Hamad Bin Khalifa University, Doha, Qatar;College of Science and Engineering, Hamad Bin Khalifa University, Doha, Qatar;Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA;Department of Biostatistics, Fielding School of Public Health, University of California Los Angeles, Los Angeles, California, USA;Department of Human Genetics, Gilbert and Rose‐Marie Ghagoury School of Medicine, Lebanese American University, Byblos, Lebanon;Institut Jérôme Lejeune, Paris, France;Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington, USA;Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington, USA;Department of Clinical Cell Biology and Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan;Genetic Medicine, Weill Cornell Medicine‐Qatar, Doha, Qatar;Institute of Human Genetics, Julius Maximilians University, Würzburg, Germany;

关键词: accelerated aging;    DNA methylation;    epigenetic clock;    Hutchinson–Gilford Progeria syndrome;    progeroid laminopathies;   

DOI  :  10.1111/acel.13555

来源: Wiley

【 授权许可】

CC BY