Epigenetic clock and methylation study of oocytes from a bovine model of reproductive aging

Aging Cell

Matthew L. Spangler¹  Joseph A. Zoller²  Caesar Z. Li²  Amin Haghani³  Steve Horvath⁴  Paweł Kordowitzki⁵  Ken Raj⁶ 

[1] Department of Animal Science, University of Nebraska, Lincoln, NE, USA;Department of Biostatistics, Fielding School of Public Health, University of California, Los Angeles, CA, USA;Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, CA, USA;Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, CA, USA;Department of Biostatistics, Fielding School of Public Health, University of California, Los Angeles, CA, USA;Institute of Animal Reproduction and Food Research of Polish Academy of Sciences, Olsztyn, Poland;Institute for Veterinary Medicine, Nicolaus Copernicus University, Torun, Poland;Radiation Effects Department, Centre for Radiation, Chemical and Environmental Hazards, Public Health England, Didcot, UK;

关键词: DNA methylation;    epigenetic clock;    epigenome‐wide association study;    oocytes;    reproductive aging;   

DOI  :  10.1111/acel.13349

来源: Wiley

【 授权许可】

CC BY