Wilms' tumour 1‐associating protein inhibits endothelial cell angiogenesis by m6A‐dependent epigenetic silencing of desmoplakin in brain arteriovenous malformation

Journal of Cellular and Molecular Medicine

Zihan Yan¹  Jie Wang¹  Hongyuan Xu¹  Hao Li¹  Jia Wang¹  Yong Cao¹  Ran Huo¹  Yimeng Xue²  Lin‐jian Wang³  Ji‐zong Zhao⁴ 

[1] China National Clinical Research Center for Neurological Diseases, Beijing, China;Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China;Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China;Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China;Savaid Medical School, University of Chinese Academy of Sciences, Beijing, China;Savaid Medical School, University of Chinese Academy of Sciences, Beijing, China;China National Clinical Research Center for Neurological Diseases, Beijing, China;Savaid Medical School, University of Chinese Academy of Sciences, Beijing, China;China National Clinical Research Center for Neurological Diseases, Beijing, China;Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China;Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China;Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China;

关键词: angiogenesis;    brain arteriovenous malformation;    desmoplakin;    m6A;    Wnt pathway;    Wilms' tumour 1‐associating protein;   

DOI  :  10.1111/jcmm.15101

来源: Wiley

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