A novel model of a biomechanically induced osteoarthritis‐like cartilage for pharmacological in vitro studies

Journal of Cellular and Molecular Medicine

Katrin Sauerland¹  Amela Wolf¹  Juergen Steinmeyer²  Manfred Schudok³ 

[1] Institute for Pharmacology and Toxicology, University of Bonn, Bonn, Germany;Institute for Pharmacology and Toxicology, University of Bonn, Bonn, Germany;Laboratory for Experimental Orthopaedics, Department of Orthopaedics, University of Giessen, Giessen, Germany;R&D, Drug Metabolism & Pharmacokinetics, Sanofi‐Aventis Deutschand GmbH, Frankfurt, Germany;

关键词: disease model;    drug;    matrix metalloproteinase inhibitor;    metabolism;    OA;    Osteoarthritis;    pharmacology;   

DOI  :  10.1111/jcmm.17044

来源: Wiley

【 授权许可】

CC BY