Proper control of R‐loop homeostasis is required for maintenance of gene expression and neuronal function during aging

Aging Cell

Alyssa Easton¹  Spencer Escobedo²  Juan Jauregui‐Lozano²  Hana Hall³  Vikki M. Weake⁴  Nadia A. Lanman⁵ 

[1] Department of Agricultural and Biological Engineering, Purdue University, West Lafayette, Indiana, USA;Department of Biochemistry, Purdue University, West Lafayette, Indiana, USA;Department of Biochemistry, Purdue University, West Lafayette, Indiana, USA;Purdue Institute for Integrative Neuroscience, Purdue University, West Lafayette, Indiana, USA;Department of Biochemistry, Purdue University, West Lafayette, Indiana, USA;Purdue University Center for Cancer Research, Purdue University, West Lafayette, Indiana, USA;Department of Comparative Pathobiology, College of Veterinary Medicine, Purdue University, West Lafayette, Indiana, USA;Purdue University Center for Cancer Research, Purdue University, West Lafayette, Indiana, USA;

关键词: aging;    Drosophila;    eye;    neurons;    photoreceptors;    R‐loop;    transcription;    visual;   

DOI  :  10.1111/acel.13554

来源: Wiley

【 授权许可】

CC BY