Case Report: Clinical Analysis of Fulminant Mycoplasma pneumoniae Pneumonia in Children

Frontiers in Pediatrics

Chunjiao Han¹  Tongqiang Zhang²  Jing Ning²  Yongsheng Xu²  Wei Guo³  Chunquan Cai⁴ 

[1] Clinical School of Paediatrics, Tianjin Medical University, Tianjin, China;Department of Pulmonology, Tianjin Children's Hospital/Tianjin University Children's Hospital, Tianjin, China;Department of Pulmonology, Tianjin Children's Hospital/Tianjin University Children's Hospital, Tianjin, China;Clinical School of Paediatrics, Tianjin Medical University, Tianjin, China;Institute of Pediatrics, Tianjin Children's Hospital/Tianjin University Children's Hospital, Tianjin, China;

关键词: Mycoplasma pneumoniae;    children;    clinical diagnosis;    fiberoptic bronchoscopy;    treatment;   

DOI  :  10.3389/fped.2021.741663

来源: Frontiers

【 摘 要 】

Fulminant Mycoplasma pneumoniae pneumonia (FMPP) accounts for 0.5–2% of all MPP cases, which is considered as MPP combined with severe complications such as hypoxemia, acute respiratory distress syndrome, or acute respiratory failure. It primarily affects young adults with no underlying disease. Although some studies have proved the severity of FMPP, the details about clinical diagnosis and treatment of FMPP in children have been rarely reported. In this case study, we described three cases who suffered from FMPP. These children not only developed acute lung injury and multiple organ involvement within 7 days of treatment, but were also found plastic bronchitis by bronchoscopy. Finally, all the patients were treated successfully with azithromycin, glucocorticoid, and bronchoscopy lavage. We conclude that this case study would contribute to raise awareness with respect to FMPP, which may occur at a younger age with faster disease progression and common extrapulmonary manifestations. It also reinforces the importance of early identification and prompt intervention to save life of children and reduces sequelae. Further studies are needed about mechanism of FMPP.

【 授权许可】

CC BY