Detection and phylogenetic analysis of a novel tick-borne virus in Haemaphysalis longicornis ticks and sheep from Shandong, China

Virology Journal

Lin Liu¹  Lijun Shao²  Shaoqing Wang²  Hengyi Sun²  Guoyu Niu²  Yongjin Wang²  Yun Gao²  Ruiheng Chang³ 

[1] Immune-Path Biotechnology (Suzhou) Co., Ltd, 215000, Suzhou, China;School of Public Health, WeiFang Medical University, 261053, Weifang, China;Tianjin International Joint Academy of Biomedicine, 300457, Tianjin, China;

关键词: Dabieshan tick virus;    Ticks;    Sheep;    Shandong Province;   

DOI  :  10.1186/s12985-021-01704-y

来源: Springer

【 摘 要 】

Dabieshan tick virus (DTV) was first identified in Haemaphysalis longicornis from Hubei Province, China in 2015. However, its pathogenic potential to animals and human remains to be further explored. In this study, a total of 170 engorged ticks and 22 sheep serum samples were collected from Taian and Yantai city, Shandong Province to investigate the presence of DTV. The results of qRT-PCR revealed the positive rate of 13.6% (3/22) in sheep serum and 8.2% (14/170) in attached ticks, respectively. Phylogenetic analysis demonstrated a close evolutionary relationship among those DTV isolates from animal and ticks, and DTV might be relatively conservative in evolution. These findings are the first to demonstrate molecular evidence of DTV in domestic animals. Nonetheless, whether or not causing disease in animals, DTV deserves further investigation.

【 授权许可】

CC BY