MMP‐7 affects peritoneal ultrafiltration associated with elevated aquaporin‐1 expression via MAPK/ERK pathway in peritoneal mesothelial cells

Journal of Cellular and Molecular Medicine

Jia Zhou¹  Zhuojun Zheng²  Qiaomu Yang³  Daming Zuo⁴  Nirong Gong⁵  Zhiwen Xiao⁵  Jun Ai⁵  Fen Zhang⁵  Yue Yin⁶ 

[1] Department of Immunology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China;Department of Medical Laboratory, School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou, China;Department of Medical Laboratory, School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou, China;Department of Immunology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China;Department of Medical Laboratory, School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou, China;Microbiome Medicine Center, Zhujiang Hospital, Southern Medical University, Guangzhou, China;Division of Nephrology, State Key Laboratory of Organ Failure Research, National Clinical Research Center of Kidney Disease, Guangdong Provincial Key Laboratory of Renal Failure Research, Guangzhou Regenerative Medicine and Health Guangdong Laboratory, Nanfang Hospital, Southern Medical University, Guangzhou, China;Division of Nephrology, State Key Laboratory of Organ Failure Research, National Clinical Research Center of Kidney Disease, Guangdong Provincial Key Laboratory of Renal Failure Research, Guangzhou Regenerative Medicine and Health Guangdong Laboratory, Nanfang Hospital, Southern Medical University, Guangzhou, China;Department of Medical Laboratory, School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou, China;

关键词: aquaporin‐1;    extracellular signal‐regulated kinase;    matrix metalloproteinases‐7;    peritoneal membrane dysfunction;    ultrafiltration failure;   

DOI  :  10.1111/jcmm.16697

来源: Wiley

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