Axl‐inhibitor bemcentinib alleviates mitochondrial dysfunction in the unilateral ureter obstruction murine model

Journal of Cellular and Molecular Medicine

Gro Gausdal¹  James B. Lorens²  Fredrik Hoel³  Karl Johan Tronstad³  August Hoel⁴  Tony Chen⁴  Tarig Osman⁴  Hassan Elsaid⁴  Lea Landolt⁴  Hans‐Peter Marti⁵  Jessica Furriol⁵  Janka Babickova⁶ 

[1] BerGenBio ASA, Bergen, Norway;BerGenBio ASA, Bergen, Norway;Department of Biomedicine, Center for Cancer Biomarkers, University of Bergen, Bergen, Norway;Department of Biomedicine, University of Bergen, Bergen, Norway;Department of Clinical Medicine, University of Bergen, Bergen, Norway;Department of Clinical Medicine, University of Bergen, Bergen, Norway;Department of Medicine, Haukeland University Hospital, Bergen, Norway;Department of Clinical Medicine, University of Bergen, Bergen, Norway;Faculty of Medicine, Institute of Molecular Biomedicine, Comenius University in Bratislava, Bratislava, Slovakia;

关键词: AXL inhibition;    bemcentinib;    mitochondria;    oxidative stress;    renal fibrosis;    UUO model;   

DOI  :  10.1111/jcmm.16769

来源: Wiley

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