Hypoxia blocks ferroptosis of hepatocellular carcinoma via suppression of METTL14 triggered YTHDF2‐dependent silencing of SLC7A11

Journal of Cellular and Molecular Medicine

Guowei Yang¹  Zhuoyang Fan¹  Wei Zhang¹  Jianhua Wang¹  Ligang Xu¹  Pingping Liu¹  Zhiping Yan¹  Rong Liu²  Minfeng Shu³  Qian Liu³  Guangqin Liu³  Hong Han⁴ 

[1] Department of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai, China;Department of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai, China;Department of Interventional Radiology, Xiamen Branch, Zhongshan Hospital, Fudan University, Shanghai, China;Department of Pharmacology, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, China;Department of Ultrasound, Zhongshan Hospital of Fudan University, Shanghai, China;

关键词: ferroptosis;    hepatocellular carcinoma;    hypoxia;    METTL14;    SLC7A11;   

DOI  :  10.1111/jcmm.16957

来源: Wiley

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