Changing and stable chromatin accessibility supports transcriptional overhaul during neural stem cell activation and is altered with age

Aging Cell

Shleshma Dhakal¹  Abigail K. Brown¹  Sun Y. Maybury‐Lewis¹  Mitchell Yeary¹  Ashley E. Webb²  Anna Sloutskin³  Tamar Juven‐Gershon³ 

[1] Department of Molecular Biology, Cell Biology, and Biochemistry, Brown University, Providence, Rhode Island, USA;Department of Molecular Biology, Cell Biology, and Biochemistry, Brown University, Providence, Rhode Island, USA;Carney Institute for Brain Science, Brown University, Providence, Rhode Island, USA;Center on the Biology of Aging, Brown University, Providence, Rhode Island, USA;The Mina and Everard Goodman Faculty of Life Sciences, Bar‐Ilan University, Ramat Gan, Israel;

关键词: aging;    chromatin accessibility;    neural stem cells;    stem cell activation;   

DOI  :  10.1111/acel.13499

来源: Wiley

【 授权许可】

CC BY