Oxidized LDL‐dependent pathway as new pathogenic trigger in arrhythmogenic cardiomyopathy

EMBO Molecular Medicine

Mattia Chiesa¹  Lorenzo Arnaboldi²  Simona De Metrio²  Alberto Corsini³  Marina Camera⁴  Werner Rauhe⁵  Michela Casella⁶  Corrado Carbucicchio⁶  Valentina Catto⁶  Antonio Dello Russo⁶  Claudio Tondo⁷  Eva König⁸  Monica De Musso⁸  Viviana Meraviglia⁸  Chiara Volani⁸  Giada Cattelan⁸  Alessandra Rossini⁸  Matteo Pedrazzini⁹  Walter Birchmeier^1,10  Adolfo Paolin^1,11  Elisa Cogliati^1,11  Saima Mushtaq^1,12  Edoardo Conte^1,12  Daniele Andreini^1,13  Benedetta Porro^1,14  Linda Turnu^1,14  Ilaria Stadiotti^1,15  Manuel Casaburo^1,15  Elena Sommariva^1,15  Alessandro Scopece^1,15  Giulio Pompilio^1,16  Giuseppina Milano^1,17 

[1] Bioinformatics and Artificial Intelligence facility, Centro Cardiologico Monzino IRCCS, Milan, Italy;Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, Milan, Italy;Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, Milan, Italy;IRCCS MultiMedica, Milan, Italy;Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, Milan, Italy;Unit of Cell and Molecular Biology in Cardiovascular Diseases, Centro Cardiologico Monzino IRCCS, Milan, Italy;General Hospital Bolzano/Bozen, Bolzano, Italy;Heart Rhythm Center, Centro Cardiologico Monzino IRCCS, Milan, Italy;Heart Rhythm Center, Centro Cardiologico Monzino IRCCS, Milan, Italy;Department of Biomedical, Surgical and Dental Sciences, Università degli Studi di Milano, Milan, Italy;Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck, Bozen, Italy;Laboratory of Cardiovascular Genetics, Istituto Auxologico Italiano, IRCCS, Milan, Italy;Max Delbrück Center for Molecular Medicine, Berlin‐Buch, Germany;Treviso Tissue Bank Foundation, Treviso, Italy;Unit of Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy;Unit of Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy;Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy;Unit of Metabolomics and Cellular Biochemistry of Atherothrombosis, Centro Cardiologico Monzino IRCCS, Milan, Italy;Unit of Vascular Biology and Regenerative Medicine, Centro Cardiologico Monzino IRCCS, Milan, Italy;Unit of Vascular Biology and Regenerative Medicine, Centro Cardiologico Monzino IRCCS, Milan, Italy;Department of Biomedical, Surgical and Dental Sciences, Università degli Studi di Milano, Milan, Italy;Unit of Vascular Biology and Regenerative Medicine, Centro Cardiologico Monzino IRCCS, Milan, Italy;Department of Heart and Vessels, Laboratory of Cardiovascular Research, University Hospital of Lausanne, Lausanne, Switzerland;

关键词: Arrhythmogenic Cardiomyopathy;    ARVC;    adipogenesis;    oxidative stress;    lipoproteins;   

DOI  :  10.15252/emmm.202114365

来源: Wiley

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