Down‐regulation of miR‐200c attenuates AngII‐induced cardiac hypertrophy via targeting the MLCK‐mediated pathway

Journal of Cellular and Molecular Medicine

Shun Wang¹  Beilei Liu¹  Gang Wu¹  Congxin Huang¹  Shan Hu¹  Hong Jiang¹  Xin Guo²  Mian Cheng³ 

[1]Department of Cardiology, Renmin Hospital of Wuhan University, Cardiovascular Research Institute, Wuhan University, Hubei Key Laboratory of Cardiology, Wuhan, China

[2]Department of Cardiology, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

[3]Department of Geriatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

关键词: apoptosis;    cardiac hypertrophy;    miR‐200c;    myosin light chain kinase;    reactive oxygen species;   

DOI  :  10.1111/jcmm.14135

来源: Wiley

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