Influence of CYP2D6 and CYP3A5 Polymorphisms on the Pharmacokinetics and Pharmacodynamics of Bisoprolol in Hypertensive Chinese Patients

Frontiers in Medicine

Chung Shun Ho¹  Alice P. S. Kong²  Tanya T. W. Chu²  Brian Tomlinson³  Sze Wa Chan⁴  Weiwei Zeng⁵ 

[1] Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, China;Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, China;Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, China;Faculty of Medicine, Macau University of Science and Technology, Macau, China;School of Health Sciences, Caritas Institute of Higher Education, Hong Kong, China;Shenzhen Baoan Women's and Children's Hospital, Jinan University, Shenzhen, China;

关键词: bisoprolol;    blood pressure;    CYP2D6;    CYP3A5;    pharmacokinetics;    polymorphisms;   

DOI  :  10.3389/fmed.2021.683498

来源: Frontiers

【 授权许可】

CC BY