Symptomatic SARS-COV-2 reinfection: healthcare workers and immunosuppressed individuals at high risk

BMC Infectious Diseases

Xóchitl Trujillo¹  Miguel Huerta¹  Mónica Ríos-Silva²  Efrén Murillo-Zamora³  Oliver Mendoza-Cano⁴  Felipe Aguilar-Sollano⁵ 

[1] Centro Universitario de Investigaciones Biomédicas, Universidad de Colima, Av. 25 de julio 965, Col. Villas San Sebastián, C.P. 28045, Colima, México;Centro Universitario de Investigaciones Biomédicas, Universidad de Colima, Av. 25 de julio 965, Col. Villas San Sebastián, C.P. 28045, Colima, México;Centro Universitario de Investigaciones Biomédicas, Universidad de Colima - Cátedras CONACyT, Av. 25 de julio 965, Col. Villas San Sebastián, C.P. 28045, Colima, México;Departamento de Epidemiología, Unidad de Medicina Familiar No. 19, Instituto Mexicano del Seguro Social, Av. Javier Mina 301, Col. Centro, C.P. 28000, Colima, México;Facultad de Medicina, Universidad de Colima, Av. Universidad 333, Col. Las Víboras, C.P. 28040, Colima, México;Facultad de Ingeniería Civil, Universidad de Colima, km. 9 carretera Colima-Coquimatlán, Coquimatlán, C.P. 28400, Colima, México;Programa de Maestría en Ciencias Médicas, Universidad de Colima, Av. Universidad 333, Col. Las Víboras, C.P. 28040, Colima, México;

关键词: COVID-19;    Severe Acute Respiratory Syndrome Coronavirus 2;    Health Personnel;    Risk Reduction Behavior;   

DOI  :  10.1186/s12879-021-06643-1

来源: Springer

【 摘 要 】

BackgroundKnowledge regarding factors predicting the SARS-COV-2 reinfection risk is scarce and it has major implications in public health policies. We aimed to identify factors associated with the risk of symptomatic SARS-COV-2 reinfection.MethodsWe conducted a nationwide retrospective cohort study and 99,993 confirmed cases of COVID-19 were analyzed.ResultsThe overall risk of reinfection (28 or more elapsed days between both episodes onset) was 0.21% (incidence density, 2.5 reinfections per 100,000 person-days) and older subjects and those with the mild primary disease were at reduced risk of the event. Healthcare workers and immunosuppressed or renal patients had at greater risk of SARS-COV-2 reinfection.ConclusionsIf replicated in other populations, these results may be useful to prioritize efforts focusing on the reduction of SARS-COV-2 spread and the related burden.

【 授权许可】

CC BY