Medical cannabis in chronic pain management – Where are we now?

Indian Journal of Pain

article

Wan Jane Liew¹  Shamim Haider² 

[1] Department of Anaesthesiology and Surgical Intensive Care Singapore General Hospital Singapore;Department of Pain Management, Colchester General Hospital

关键词: Cannabinoids;    chronic pain;    medical cannabis;    pain management;   

DOI  :  10.4103/ijpn.ijpn_1_21

学科分类：分子生物学，细胞生物学和基因

来源: Medknow

【 摘 要 】

Chronic pain is a debilitating condition that afflicts a significant number of people throughout the world. The mechanisms of chronic pain remain to be fully understood, and treatment for chronic pain has remained a challenge for pain practitioners. Cannabis and cannabis‑based medicine (CBM) have emerged over the last two decades as potential treatment options for an array of medical issues, of which chronic pain is one of them. Clinical trials thus far seem to suggest that medical cannabis may have some clinical effect in reducing pain severity in chronic noncancer pain as an adjunct to standard treatment, but inherent weaknessesin the available evidence mean that the verdict for medical cannabis has yet to be set in stone. The issue of medical cannabis is further complicated by the connection of cannabis with neuropsychiatric side effects and substance misuse. Much work needs to be done by both clinicians and government bodies to translate the benefits of medical cannabis in the laboratory into positive patient outcomes at the bedside in a safe manner.

【 授权许可】

CC BY-NC-SA