Influenza vaccination should have no border: cost-effectiveness of cross-border subsidy

BMC Public Health

Alison P. Galvani¹  Meagan C. Fitzpatrick²  Edan Shahmoon³  Dan Yamin³  Dor Kahana³ 

[1]Center for Infectious Disease Modeling and Analysis, Yale School of Public Health, Yale University, 06510, New Haven, CT, USA

[2]Center for Vaccine Development and Global Health, University of Maryland School of Medicine, 21201, Baltimore, Maryland, USA

[3]Center for Infectious Disease Modeling and Analysis, Yale School of Public Health, Yale University, 06510, New Haven, CT, USA

[4]Laboratory for Epidemic Modeling and Analysis, Department of Industrial Engineering, Faculty of Engineering, Tel Aviv University, 69978, Tel Aviv, Israel

关键词: Influenza vaccination;    Transmission model;    SIR model;    Social contact;    Cost-effective analysis;   

DOI  :  10.1186/s12889-021-11601-2

来源: Springer

【 摘 要 】

BackgroundInfluenza is a substantial cause of morbidity and mortality for Israel and the Palestinian territory. Given the extensive interaction between the two populations, vaccination in one population may indirectly benefit the other via reduced transmission. Due to the mobility and extensive contacts, Palestinians employed in Israel could be a prime target for vaccination.MethodsTo evaluate the epidemiological and the economic benefits conferred by vaccinating Palestinians employed in Israel, we developed a model of influenza transmission within and between Israel and the West Bank. We parameterized the contact patterns underlying transmission by conducting a survey among Palestinians employed in Israel, and integrating survey results with traffic patterns and socio-demographic data.ResultsVaccinating 50% of Palestinian workers is predicted to reduce the annual influenza burden by 28,745 cases (95% CI: 15,031-50,717) and 37.7 deaths (95% CI: 19·9–65·5) for the Israeli population, and by 32,9900 cases (95% CI: 14,379-51,531) and 20.2 deaths (CI 95%: 9·8–31·5) for the Palestinian population. Further, we found that as the indirect protection was so substantial, funding such a vaccination campaign would be cost-saving from the Israeli Ministry of Health perspective.ConclusionsOffering influenza vaccination to Palestinians employed in Israel could efficiently reduce morbidity and mortality within both Israel and the Palestinian territory.

【 授权许可】

CC BY