Understanding and controlling filamentous growth of fungal cell factories: novel tools and opportunities for targeted morphology engineering

Fungal Biology and Biotechnology

Vera Meyer¹  Lars Barthel¹  Timothy Cairns¹  Rudibert King²  Philipp Kunz²  Heiko Briesen³  Stefan Schmideder³  Henri Müller³  Rainer Krull⁴  Anna Dinius⁴ 

[1]Chair of Applied and Molecular Microbiology, Institute of Biotechnology, Technische Universität Berlin, Straße des 17. Juni 135, 10623, Berlin, Germany

[2]Chair of Measurement and Control, Institute of Chemical and Process Engineering, Technische Universität Berlin, Straße des 17. Juni 135, 10623, Berlin, Germany

[3]Chair of Process Systems Engineering, School of Life Sciences, Technical University of Munich, Gregor- Mendel-Str. 4, 85354, Freising, Germany

[4]Institute of Biochemical Engineering, Technische Universität Braunschweig, Rebenring 56, 38106, Brunswick, Germany

[5]Center of Pharmaceutical Engineering, Technische Universität Braunschweig, Franz-Liszt-Str. 35a, 38106, Brunswick, Germany

关键词: Filamentous fungi;    Aspergillus niger;    Polar growth;    Micromorphology;    Macromorphology;    X-ray micro-computed tomography;    Pellet;    Co-expression network;    Hypothetical proteins;    Rheology;    Modelling;   

DOI  :  10.1186/s40694-021-00115-6

来源: Springer

【 授权许可】

CC BY