HTLV-2 infection in Manaus, Brazil: first description of HTLV-2c subtype in an urban area of the Western Amazon region

Sociedade Brasileira de Medicina Tropical. Revista

article

Gemilson Soares Pontes¹  Hygor Halyson Figueiredo Ribeiro¹  Diana Mota Toro²  José Pereira de Moura Neto³  Victor Souza⁴  Maria Edilene Martins de Almeida⁴  Valdinete Alves do Nascimento⁴  Cristovão Alves da Costa¹  Felipe Gomes Naveca⁴  Mike Santos⁵  Antonio Carlos Rosário Vallinoto⁵ 

[1] Instituto Nacional de Pesquisa da Amazônia, Brasil.Universidade do Estado do Amazonas, Programa de Pós-graduação Stricto Sensu em Hematologia;Universidade Federal do Amazonas;Universidade do Estado do Amazonas, Programa de Pós-graduação Stricto Sensu em Hematologia, Brasil.Universidade Federal do Amazonas;Instituto Leônidas e Maria Deane;Universidade Federal do Pará, Programa de Pós-graduação Stricto Sensu em Biologia de Agentes infecciosos e Parasitários

关键词: Prevalence;    Blood transfusion;    Phylogeny;    HTLV-2c;    Amazon region;   

DOI  :  10.1590/0037-8682-0066-2020

学科分类：农业科学（综合）

来源: Sociedade Brasileira de Medicina Tropical

【 摘 要 】

Introduction: We investigated the prevalence of human T-cell lymphotropic virus types 1 and 2 (HTLV-1/2) infection in patients with hematological diseases from the western Amazon region of Brazil. Methods: Samples from 306 patients were submitted for the molecular diagnosis of HTLV-1/2 infection by real time PCR (qPCR), with amplification, sequencing, and phylogenetic analysis of the long terminal repeat (LTR) region. Results: A 29-year-old male carrier of sickle cell anemia with a history of multiple blood transfusions was diagnosed with the HTLV-2c subtype. Conclusions: This study describes the first known occurrence of HTLV-2c in the urban area of Brazil’s western Amazon region.

【 授权许可】

CC BY