Editorial: Bio-materials for Cardiovascular Diseases

Frontiers in Cardiovascular Medicine

article

Paola Campagnolo¹  Maurizio Pesce² 

[1] Section of Cardiovascular Sciences, Faculty of Health and Medical Sciences, School of Biosciences and Medicine, University of Surrey;Unità di Ingegneria Tissutale Cardiovascolare, Istituto di Ricerca e Cura a Carattere Scientifico

关键词: biomaterials;    scaffolds;    tissue engineering;    bioimplant;    cardiovascular;   

DOI  :  10.3389/fcvm.2021.670964

学科分类：地球科学(综合)

来源: Frontiers

【 摘 要 】

The supply of transplants or autologous materials for the repair or replacement of defective cardiovascular tissues is largely inadequate and it does not fulfill the increasing demand resulting from the generalized aging of the population. Although the mortality has decreased over time thanks to improvements in prevention and new intervention protocols, the quality of life of the patients is still often poor, due to the limited regenerative capacity of the cardiovascular tissues (e.g., the myocardium) or the use of implant devices made with non-living tissues not endowed with regeneration ability (e.g., the bioprosthetic valves). In the last decades, the growth of the tissue engineering as a novel interdisciplinary framework to supply living materials able to regenerate lost tissues has made huge steps in refinement. This progress has been promoted by advancements in fabrication and refinement of biomaterials, and the possibility to combine cells with permanent or bio-absorbable scaffolds able to provide the necessary geometrical, chemical, and mechanical information to instruct proper cellular behavior. The aim of the present Research Topic was to collect experimental work and review articles illustrating improvements in the state-of-the-art for the production and application of biomaterials for the preparation of cardiac, valve, and vascular tissue replacements.

【 授权许可】

CC BY