Three-Dimensional Printing of Fetal Models of Congenital Heart Disease Derived From Microfocus Computed Tomography: A Case Series

Frontiers in Pediatrics

article

Camilla Sandrini¹  Claudio Lombardi²  Andrew I. U. Shearn³  Maria Victoria Ordonez³  Massimo Caputo³  Francesca Presti⁴  Giovanni Battista Luciani⁵  Lucia Rossetti¹  Giovanni Biglino³ 

[1] Division of Cardiology, Department of Medicine, University of Verona;Studio Diagnostico Eco;Bristol Medical School, Bristol Heart Institute, University of Bristol, United Kingdom;Division of Obstetrics and Gynecology B, Department of Surgery, University of Verona;Division of Cardiac Surgery, Department of Surgery, University of Verona;National Heart and Lung Institute, Imperial College London, United Kingdom

关键词: 3D printing;    microfocus computed tomography;    fetal heart;    congenital heart disease;    fetal cardiology;    prenatal diagnosis;   

DOI  :  10.3389/fped.2019.00567

学科分类：社会科学、人文和艺术（综合）

来源: Frontiers

【 摘 要 】

This article presents a case series of n = 21 models of fetal cardiovascular anatomies obtained from post mortem microfocus computed tomography (micro-CT) data. The case series includes a broad range of diagnoses (e.g., tetralogy of Fallot, hypoplastic left heart syndrome, dextrocardia, double outlet right ventricle, atrio-ventricular septal defect) and cases also had a range of associated extra-cardiac malformations (e.g., VACTERL syndrome, central nervous system anomalies, renal anomalies). All cases were successfully reconstructed from the microfocus computed tomography data, demonstrating the feasibility of the technique and of the protocols, including in-house printing with a desktop 3D printer (Form2, Formlabs). All models were printed in 1:1 scale as well as with the 5-fold magnification, to provide insight into the intra-cardiac structures. Possible uses of the models include education and training.

【 授权许可】

CC BY