Case Report: Analysis of Inflammatory Cytokines IL-6, CCL2/MCP1, CCL5/RANTES, CXCL9/MIG, and CXCL10/IP10 in a Cystic Fibrosis Patient Cohort During the First Wave of the COVID-19 Pandemic

Frontiers in Pediatrics

article

Giulia Baresi¹  Raffaele Badolato²  Mauro Giacomelli¹  Daniele Moratto³  Marco Chiarini³  Immacolata Claudia Conforti¹  Rita Padoan¹  Piercarlo Poli²  Silviana Timpano²  Francesca Caldarale¹ 

[1] Pediatrics Clinic, “Angelo Nocivelli” Institute of Molecular Medicine, Brescia University;Cystic Fibrosis Regional Support Center;Clinical Chemistry Laboratory

关键词: SARS-CoV-2 infection;    T cell activation;    inflammatory activation;    cystic fibrosis;    cytokines;   

DOI  :  10.3389/fped.2021.645063

学科分类：社会科学、人文和艺术（综合）

来源: Frontiers

【 摘 要 】

Since the beginning of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, data registered in the European countries revealed increasing cases of infection in cystic fibrosis (CF) patients. In the course of this pandemic, we enrolled 17 CF patients for a study evaluating inflammatory markers. One of them developed COVID - 19, giving us the possibility to analyze inflammatory markers in the acute phase as compared to levels detected before and after the infectious episode and to levels measured in the other CF patients enrolled to the study who did not experience COVID-19 and 23 patients referred to our center for SARS-CoV-2 infection.

【 授权许可】

CC BY