Characteristics and Indications of Kawasaki Disease Among Infants Under 6 Months

Frontiers in Pediatrics

article

Yunjia Tang¹  Ye Chen¹  Wenhua Yan¹  Qiuqin Xu¹  Haitao Lv¹ 

[1] Department of Cardiology, Children's Hospital of Soochow University

关键词: Kawasaki disease;    characteristics;    infants;    indications;    urinary tract infection;    adenovirus infection;   

DOI  :  10.3389/fped.2020.00470

学科分类：社会科学、人文和艺术（综合）

来源: Frontiers

【 摘 要 】

Objectives: To explore the characteristics of Kawasaki disease (KD) under 6 months and to investigate the possible indications of incomplete KD (iKD). Methods: The medical records of KD patients hospitalized in Children's Hospital of Soochow University from January 2007 to December 2017 were retrospectively reviewed and analyzed. A total of 50 cases of urinary tract infection (UTI) and 50 cases of adenovirus (ADV)-infected patients under 6 months that were age and gender-matched with the main complaint of high fever were selected as controls. Results: A total of 1,872 KD patients were enrolled. Among them, 194 (10.4%) were infantile patients under 6 months. There were 72 (37.1%) and 494 (29.4%) iKD in patients younger and older than 6 months, respectively ( P 22.7 mg/L, N% > 47.4 and PLT > 496 × 10 9 /L were indications of iKD when compared with ADV infection (area under the curve [AUC]: 0.872, 0.939, 0.707, and 0.684, respectively). N% > 51.8 and albumin < 39.0 g/L were indications of iKD when compared with UTI (AUC: 0.627 and 0.832, respectively). Conclusions: Infantile KD patients under 6 months had their own particularity. Laboratory variables could be good indications of iKD when compared with UTI and ADV infection.

【 授权许可】

CC BY