Presentation and Outcomes of Kawasaki Disease in Latin American Infants Younger Than 6 Months of Age: A Multinational Multicenter Study of the REKAMLATINA Network

Frontiers in Pediatrics

article

Elizabeth Moreno¹  Dora Estripeaut²  Kathia Luciani³  Francisco J. Rodríguez-Quiroz⁴  Olguita del Aguila⁵  Germán Camacho-Moreno⁶  Virgen Gómez⁷  Tamara Viviani⁸  Martha I. Alvarez-Olmos⁹  Heloisa Helena de Souza Marques^1,10  Enrique Faugier-Fuentes^1,11  S. Diana Garcia¹  Patricia Saltigeral-Simental^1,12  Eduardo López-Medina^1,13  Greta Miño-León^1,14  Sandra Beltrán^1,15  Lucila Martínez-Medina^1,16  Maria C. Pirez^1,17  Fernanda Cofré^1,18  Adriana H. Tremoulet¹  Emelia Bainto¹  Andrea P. Salgado^1,19  Austin Parish¹  Benjamin D. Rosellini¹  Rolando Ulloa-Gutierrez^2,21  Luis M. Garrido-Garcia^1,12  Lourdes Dueñas^2,22 

[1] California/Rady Children's Hospital San Diego, University of California, United States;Hospital del Niño Dr. José Renán Esquivel;Hospital de Especialidades Pediátricas Omar Torrijos Herrera;Instituto Hondureño de Seguridad Social;Hospital Nacional Edgardo Rebagliati Martins;Fundación HOMI Hospital Pediátrico de la Misericordia and Universidad Nacional de Colombia;Centro Médico Universidad Central del Este;Hospital Sotero del Río;Fundación Cardioinfantil and Universidad El Bosque;Hospital Das Clinicas da Faculdade Medicina da USP;Hospital Infantil de México Federico Gómez;Hospital Infantil Privado & Instituto Nacional de Pediatría;Hospital Universitario del Valle & Centro Médico Imbanaco and Clínica Farallones;Hospital del Niño “Dr. Francisco de Icaza Bustamante”;Servicio de Infectología, Clínica Colsanitas;Centenario Hospital Miguel Hidalgo;Hospital Pediátrico Centro Hospitalario Pereira Rossell;Hospital Roberto del Río;Pontificia Universidad Católica de Chile;Meta-Research Innovation Center at Stanford University, United States;Hospital Nacional de Niños Dr. Carlos Sáenz Herrera;Hospital de Niños Benjamín Bloom

关键词: Kawasaki disease;    Latin America;    infants;    coronary artery abnormalities;    delayed diagnosis;   

DOI  :  10.3389/fped.2020.00384

学科分类：社会科学、人文和艺术（综合）

来源: Frontiers

【 摘 要 】

Objective: To characterize the clinical presentation and outcomes of Kawasaki disease (KD) in infants 10 days (50 vs. 7.4%, P = 0.043)]. Conclusion: Our data show that despite treatment in the first 10 days of illness, infants <6 months of age in Latin America have a higher risk of developing a coronary artery aneurysm. Delay in the diagnosis leads to larger coronary artery aneurysms disproportionately in these infants. Thus, suspicion for KD should be high in this vulnerable population.

【 授权许可】

CC BY