Frailty Pathogenesis, Assessment, and Management in Older Adults With COVID-19

Frontiers in Medicine

article

Quan She¹  Min Li¹  Weihong Zhao¹  Jianqing Wu¹ 

[1] Department of Geriatrics, Jiangsu Provincial Key Laboratory of Geriatrics, First Affiliated Hospital, Nanjing Medical University

关键词: COVID-19;    frailty;    pathogenesis;    assessment;    management;   

DOI  :  10.3389/fmed.2021.694367

学科分类：社会科学、人文和艺术（综合）

来源: Frontiers

【 摘 要 】

The 2019 coronavirus disease (COVID-19) is a highly contagious and deadly disease. The elderly people are often accompanied by chronic inflammation and immunodeficiency, showing a frail state. The strength, endurance, and physiological function of the elderly are significantly decreased, and the ability to deal with stress response is weakened. They are the high-risk group that suffering from COVID-19, and rapidly developing to critical illness. Several recent studies suggest that the incidence rate of COVID-19 in elderly patients with frailty is high. Early assessment, detection, and effective intervention of frailty in COVID-19 patients are conducive to significantly improve the quality of life and improve prognosis. However, there are insufficient understanding and standards for the current evaluation methods, pathogenesis and intervention measures for COVID-19 combined with frailty. This study reviews the progress of the research on the potential pathogenesis, evaluation methods and intervention measures of the elderly COVID-19 patients with frailty, which provides a reference for scientific and reasonable comprehensive diagnosis and treatment in clinical.

【 授权许可】

CC BY