Challenges Caused by Imported Cases Abroad for the Prevention and Control of COVID-19 in China

Frontiers in Medicine

article

Jianfei Zhu¹  Miaomiao Wen¹  Hongtao Wang²  Zhipei Zhang¹  Wuping Wang¹  Jinbo Zhao¹  Tao Jiang¹  Qingqing Zhang³  Chenghui Jia¹  Shuonan Xu⁴  Jie Lei¹  Jiakuan Chen¹  Yanmin Xia¹  Wenchen Wang¹  Xuejiao Wang¹ 

[1] Department of Thoracic Surgery, Tangdu Hospital, Air Force Military Medical University (Fourth Military Medical University);Department of Thoracic Surgery, Shaanxi Provincial People's Hospital;Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Xi'an Medical University;Department of Cardiothoracic Surgery, The First Affiliated Hospital of Xi'an Medical University

关键词: COVID-19;    global pandemic;    imported case;    epidemiological characteristics;    prevention;   

DOI  :  10.3389/fmed.2021.573726

学科分类：社会科学、人文和艺术（综合）

来源: Frontiers

【 摘 要 】

Background: Overseas imported cases of COVID-19 continue to increase in China, so we conducted this study to review the epidemiological characteristics of these patients. Methods: From February 26 to April 4, 2020, the imported cases from abroad were enrolled in this study. The effect of prevention countermeasures in curbing the spread of COVID-19 was assessed in this study. Moreover, we defined incubation period and confirmed time as from the date of leaving the epicenter to date of symptom onset and date of final diagnosed, respectively, and the interval of symptom onset to final diagnosed time was defined as diagnostic time. Categorical variables were summarized as numbers and percentages, and the difference among the variables were analyzed. Results: For 670 cases imported from abroad, 555 were Chinese and 115 were foreigners. Apparently, confirmed cases had significantly decreased after China was compelled to temporarily suspend the entry of foreign passport holders with valid visas or residence permits; 6 days after implement of controlled measures, the daily new confirmed cases were reduced to 13 cases. Moreover, about 84.3% of patients (166/197) presented symptoms 1 week after leaving the epicenter, and notably seven patients (3.6%) had symptoms 2 weeks after leaving the epicenter. The median incubation period was 3.0 days (inter quartile range, 1.0 to 6.0), the 95th percentile was 11.6 days. Additionally, most of cases (92.9%) were detected positively of nucleic acid after symptom onset with 4 days, the median diagnostic time was 2.0 days (interquartile range, 1.0 to 3.0), and the 95th percentile of the distribution was 5.0 days. Finally, about 5.8% of patients were healthy carriers, and the median confirmed time of asymptomatic patients was 4.0 days (interquartile range, 2.0 to 9.0). The following variables might be associated with confirmed time: symptom type ( P = 0.005), exported regions ( P < 0.001), and symptom onset time ( P < 0.001). Conclusions: The prevention countermeasures for imported cases implemented by the Chinese government played an indispensable role in curbing the spread of COVID-19; the time of departure from epicenter could provide an estimate of the incubation period; and a confirmed time, 2-week quarantine period might need to be prolonged, while asymptomatic patients should be closely monitored.

【 授权许可】

CC BY