期刊论文详细信息
Frontiers in Medicine
COVID-19 Therapy: Could a Copper Derivative of Chlorophyll a Be Used to Treat Lymphopenia Associated With Severe Symptoms of SARS-CoV-2 Infection?
article
Nicole F. Clark1  Andrew W. Taylor-Robinson3 
[1] Institute for Applied Ecology, University of Canberra;Centre for Marine Bioproducts Development, College of Medicine and Public Health, Flinders University;Infectious Diseases Research Group, School of Health, Medical and Applied Sciences, Central Queensland University;College of Health and Human Sciences, Charles Darwin University
关键词: chlorophyll;    therapy;    lymphopenia;    SARS-CoV-2;    COVID-19;    coronavirus;    sodium copper chlorophyllin;   
DOI  :  10.3389/fmed.2021.620175
学科分类:社会科学、人文和艺术(综合)
来源: Frontiers
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【 摘 要 】

Chlorophyll a is a specific form of chlorophyll involved in oxygenic photosynthesis. It contains a magnesium ion surrounded by a large ring structure known as a chlorin. Four nitrogen atoms from the chlorin encase and bind the magnesium atom. The magnesium center uniquely defines the molecule as chlorophyll a (1). In order to harness the widely acknowledged therapeutic benefits of chlorophyll a, a chemical process known as re-greening must occur whereby the central atom is replaced with another metal yielding the same electrostatic charge, such as zinc or copper (2). Dietary chlorophyll, a formulation derived from sodium copper chlorophyllin (SCC), is a popular dietary supplement taken by health-conscious consumers (3, 4). Chlorophyll a derivatives including SCC are known to have a number of benefits when taken at therapeutic doses (3, 5). They are non-toxic, highly soluble compounds that are demonstrated to have higher uptake in human cell systems which likely triggers the chelation of ionic compounds (6, 7).

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