Frontiers in Medicine | |
Spirometry in Central Asian Lowlanders and Highlanders, a Population Based Study | |
article | |
Stefanie Ulrich1  Michael Furian1  Bermet Estebesova2  Nurgul Toktogulova3  Gulnara Beishekeeva3  Silvia Ulrich1  Peter G. J. Burney4  Talant M. Sooronbaev2  Konrad E. Bloch1  | |
[1] Department of Respiratory Medicine, University Hospital Zurich;Department of Respiratory Medicine, National Center for Cardiology and Internal Medicine;Therapy 1 Department, Medical Faculty, Kyrgyz-Russian Slavic University;Population Health and Occupational Disease, National Heart and Lung Institute & MRC-PHE Centre for Environment and Health, Imperial College London, United Kingdom | |
关键词: spirometry; altitude; lung function; Central Asian; highlanders; | |
DOI : 10.3389/fmed.2019.00308 | |
学科分类:社会科学、人文和艺术(综合) | |
来源: Frontiers | |
【 摘 要 】
Introduction: The purpose of the study was to establish spirometric reference values for a Central Asian population of highlanders and lowlanders. Methods: Spirometries from a population-based cross-sectional study performed in 2013 in rural areas of Kyrgyzstan were analyzed. Using multivariable linear regression, Global Lung Function Initiative (GLI) equations were fitted separately for men and women, and altitude of residence (700–800 m, 1,900–2,800 m) to data from healthy, never-smoking Kyrgyz adults. The general GLI equation was applied: Predicted value = e a 0 + a 1 × ln ( Height ) + a 2 × ln ( Age ) + b 1 × ln ( Age 100 ) + b 2 × ln ( Age 100 ) 2 + b 3 × ln ( Age 100 ) 3 + b 4 × ln ( Age 100 ) 4 + b 5 × ln ( Age 100 ) 5.
【 授权许可】
CC BY
【 预 览 】
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