Microbial Resistance Movements: An Overview of Global Public Health Threats Posed by Antimicrobial Resistance, and How Best to Counter

Frontiers in Public Health

article

Sameer Dhingra¹  Nor Azlina A. Rahman²  Ed Peile³  Motiur Rahman⁴  Massimo Sartelli⁶  Mohamed Azmi Hassali⁷  Tariqul Islam⁸  Salequl Islam⁹  Mainul Haque^1,10 

[1] School of Pharmacy, Faculty of Medical Sciences, The University of the West Indies;Department of Physical Rehabilitation Sciences, Kulliyyah of Allied Health Sciences, International Islamic University Malaysia;Warwick Medical School, University of Warwick, United Kingdom;Oxford University Clinical Research Unit, Wellcome Trust Asia Programme, The Hospital for Tropical Diseases;Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, Oxford University, United Kingdom;Department of General and Emergency Surgery, Macerata Hospital;School of Pharmaceutical Sciences, Universiti Sains Malaysia;UChicago Research Bangladesh;Department of Microbiology, Jahangirnagar University;The Unit of Pharmacology, Faculty of Medicine and Defence Health, National Defence University of Malaysia

关键词: antibiotics;    antimicrobial resistance;    AMR;    globe;    public health;    hazard;   

DOI  :  10.3389/fpubh.2020.535668

学科分类：社会科学、人文和艺术（综合）

来源: Frontiers

【 摘 要 】

Antibiotics changed medical practice by significantly decreasing the morbidity and mortality associated with bacterial infection. However, infectious diseases remain the leading cause of death in the world. There is global concern about the rise in antimicrobial resistance (AMR), which affects both developed and developing countries. AMR is a public health challenge with extensive health, economic, and societal implications. This paper sets AMR in context, starting with the history of antibiotics, including the discovery of penicillin and the golden era of antibiotics, before exploring the problems and challenges we now face due to AMR. Among the factors discussed is the low level of development of new antimicrobials and the irrational prescribing of antibiotics in developed and developing countries. A fundamental problem is the knowledge, attitude, and practice (KAP) regarding antibiotics among medical practitioners, and we explore this aspect in some depth, including a discussion on the KAP among medical students. We conclude with suggestions on how to address this public health threat, including recommendations on training medical students about antibiotics, and strategies to overcome the problems of irrational antibiotic prescribing and AMR.

【 授权许可】

CC BY