Atomic force microscopy comparative analysis of the surface roughness of two posterior chamber phakic intraocular lens models: ICL versus IPCL

BMC Ophthalmology

Cesar Villa-Collar¹  Montserrat Garcia-Gonzalez²  Juan Gros-Otero³  Santiago Casado⁴  Samira Ketabi⁵  Rafael Cañones-Zafra⁵  Miguel A. Teus⁶ 

[1] Clínica Novovisión, Paseo de la Castellan, Madrid, Spain;Universidad Europea, Madrid, Spain;Clínica Rementería, Calle Almagro, 36, Madrid, Spain;Clínica Novovisión, Paseo de la Castellan, Madrid, Spain;Clínica Rementería, Calle Almagro, 36, Madrid, Spain;Universidad CEU San Pablo, Campus Montepríncipe, Madrid, Spain;Facultad de Ciencia e Ingeniería de Alimentos, Universidad Técnica de Ambato, Ambato, Ecuador;IMDEA-Nanociencia, Campus Universitario de Cantoblanco, 28049, Madrid, Spain;Hospital Universitario Príncipe de Asturias, Carretera Meco s/n, Madrid, Spain;Hospital Universitario Príncipe de Asturias, Carretera Meco s/n, Madrid, Spain;Clínica Novovisión, Paseo de la Castellan, Madrid, Spain;

关键词: Phakic intraocular lens;    ICL;    iPCL;    Atomic force microscopy;    Surface roughness;   

DOI  :  10.1186/s12886-021-02039-6

来源: Springer

【 摘 要 】

BackgroundTo compare the anterior surface roughness of two commercially available posterior chamber phakic intraocular lenses (IOLs) using atomic force microscopy (AFM).MethodsFour phakic IOLs were used for this prospective, experimental study: two Visian ICL EVO+ V5 lenses and two iPCL 2.0 lenses. All of them were brand new, were not previously implanted in humans, were monofocal and had a dioptric power of − 12 diopters (D). The anterior surface roughness was assessed using a JPK NanoWizard II® atomic force microscope in contact mode immersed in liquid. Olympus OMCL-RC800PSA commercial silicon nitride cantilever tips were used. Anterior surface roughness measurements were made in 7 areas of 10 × 10 μm at 512 × 512 point resolution. The roughness was measured using the root-mean-square (RMS) value within the given regions.ResultsThe mean of all anterior surface roughness measurements was 6.09 ± 1.33 nm (nm) in the Visian ICL EVO+ V5 and 3.49 ± 0.41 nm in the iPCL 2.0 (p = 0.001).ConclusionIn the current study, we found a statistically significant smoother anterior surface in the iPCL 2.0 phakic intraocular lenses compared with the VISIAN ICL EVO+ V5 lenses when studied with atomic force microscopy.

【 授权许可】

CC BY