Long non-coding RNA ANRIL promotes homologous recombination-mediated DNA repair by maintaining ATR protein stability to enhance cancer resistance

Molecular Cancer

Yuanyuan Chen¹  Tingting Liu¹  Yijuan Huang¹  Fu Gao¹  Yanyong Yang¹  Bailong Li¹  Hui Shen¹  Jianguo Cui¹  Kun Cao¹  Lei Liu²  Jianming Cai³ 

[1] Department of Radiation Medicine, Faculty of Naval Medicine, Naval Medical University, 800, Xiangyin Road, 200433, Shanghai, P. R. China;Department of Radiation Medicine, Faculty of Naval Medicine, Naval Medical University, 800, Xiangyin Road, 200433, Shanghai, P. R. China;Department of Oncology, General Hospital of Central Theater Command of Chinese People’s Liberation Army, No.627 Wuluo Road, Wuchang District, 430070, Wuhan, Hubei, P. R. China;Department of Radiation Medicine, Faculty of Naval Medicine, Naval Medical University, 800, Xiangyin Road, 200433, Shanghai, P. R. China;School of Public Health and Management, Wenzhou Medical University, University Town, Wenzhou, Zhejiang, P. R. China;

关键词: Long non-coding RNA;    Cancer resistance;    DNA damage repair;    ATR;   

DOI  :  10.1186/s12943-021-01382-y

来源: Springer

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