All-metal terahertz metamaterial biosensor for protein detection

Nanoscale Research Letters

Jianjun Liu¹  Zhi Hong¹  Tingting Lang²  Gangqi Wang²  Jianyuan Qin³  Fengjie Zhu⁴ 

[1]Centre for THz Research, China Jiliang University, 310018, Hangzhou, China

[2]Institute of Optoelectronic Technology, China Jiliang University, 310018, Hangzhou, China

[3]Lab of Terahertz Photonics, China Jiliang University, 310018, Hangzhou, China

[4]Zhejiang Chinese Medical University, Hangzhou, China

关键词: Bovine serum albumin;    All-metal metamaterials;    Terahertz;    Biosensors;   

DOI  :  10.1186/s11671-021-03566-3

来源: Springer

【 摘 要 】

In this paper, a terahertz (THz) biosensor based on all-metal metamaterial is theoretically investigated and experimentally verified. This THz metamaterial biosensor uses stainless steel materials that are manufactured via laser-drilling technology. The simulation results show that the maximum refractive index sensitivity and the figure of merit of this metamaterial sensor are 294.95 GHz/RIU and 4.03, respectively. Then, bovine serum albumin was chosen as the detection substance to assess this biosensor’s effectiveness. The experiment results show that the detection sensitivity is 72.81 GHz/(ng/mm2) and the limit of detection is 0.035 mg/mL. This THz metamaterial biosensor is simple, cost-effective, easy to fabricate, and has great potential in various biosensing applications.

【 授权许可】

CC BY