A short review of the genes involved in the development and progression of colorectal cancer

Biocell

article

AMAYNA ZAKARIA¹  SYED ABDULLAH IBN ASADUZZAMAN¹  ZOBAYDA NAHAR¹  HAFSA JARIN SNIGDHA¹  TASKINA MURSHED¹  RASHED NOOR¹ 

[1] Department of Life Sciences, School of Environment and Life Sciences, Independent University

关键词: Colorectal cancer;    Genes;    Signal transduction pathways;   

DOI  :  10.32604/biocell.2021.014704

学科分类：仪器

来源: Biocell

【 摘 要 】

The extent and aggression of colorectal cancer is a worldwide public health threat. Extensive research has been conducted on the pre-requisites leading to this fatal cancer. An array of genes along with their mutations and the signal transduction pathways leading to the cellular transformation into the cancerous cells have been investigated. Based on the knowledge gained so far, present review shortly discussed the role of the major genes especially those are involved in instigating abnormalities in the cellular cycles, cellular proliferation and differentiation. A simple but novel molecular scheme of the colorectal cancer development has also been plotted.

【 授权许可】

CC BY