Can electrophysiological tests be used as screening tools in detection of cognitive impairment in obstructive sleep apnea hypopnea syndrome?

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery

article

Nada, Mona M.¹  Maher, Eman A.¹  Basheer, Mye A.¹  El-Mekkawy, Leqaa A.¹ 

[1] Clinical Neurophysiology Unit, Faculty of Medicine, KasrAlainy Hospital, Cairo University

关键词: Obstructive sleep apnea;    Cognitive impairment;    Event related potentials;    Quantitative EEG;    Cognitive screening tests;   

DOI  :  10.1186/s41983-020-00163-6

学科分类：医学（综合）

来源: Springer

【 摘 要 】

One of the most prevalent sleep disorders is obstructive sleep apnea (OSA). Patients with OSA have increased risk of car and work place accidents which may be attributed to cognitive impairment due to poor sleep quality. Thus, there is an increasing need to implement simple, reliable and rapid screening for cognitive impairment in OSA patients. To assess auditory event-related potentials (ERPs) and quantitative electroencephalography (QEEG) as screening tools for detection of cognitive impairment in OSA patients taking circadian effects into consideration. Twenty OSA patients as well as 20 gender- and age-matched volunteers were subjected to trail making test (TMT), auditory ERPs and QEEG before and after at least 6 h polysomnographic recording. Correlating electrophysiological tools with TMT and clinical parameters was done as well Statistically significant changes in P300 latency and reaction time, in addition to occipital alpha power were noted in cases; however, TMT failed to detect such changes. Electrophysiological results were not constantly correlated to clinical parameters. Auditory ERPs and QEEG before and after polysomnography can be of benefit as cognitive screening test for suspected cognitive impairment in OSA patients.

【 授权许可】

CC BY