A Review of Prostanoid Receptors: Expression, Characterization, Regulation, and Mechanism of Action

Journal of Cell Communication and Signaling

article

Biringer, Roger G.¹ 

[1]College of Osteopathic Medicine, Lake Erie College of Osteopathic Medicine

关键词: receptor;    prostanoid;    eicosanoid;    prostaglandin;    G-protein;    signaling;   

DOI  :  10.1007/s12079-020-00585-0

学科分类：分子生物学，细胞生物学和基因

来源: Springer

【 摘 要 】

Prostaglandin signaling controls a wide range of biological processes from blood pressure homeostasis to inflammation and resolution thereof to the perception of pain to cell survival. Disruption of normal prostanoid signaling is implicated in numerous disease states. Prostaglandin signaling is facilitated by G-protein-coupled, prostanoid-specific receptors and the array of associated G-proteins. This review focuses on the expression, characterization, regulation, and mechanism of action of prostanoid receptors with particular emphasis on human isoforms.

【 授权许可】

CC BY