Broad geographic sampling reveals the shared basis and environmental correlates of seasonal adaptation in Drosophila

eLife

Ryan Taylor¹  Dmitri A Petrov¹  Susanne Tilk¹  Bernard Kim¹  Alan O Bergland²  Heather E Machado³  Stephen W Schaeffer⁴  Emily Behrman⁵  Katherine O'Brien⁵  Paul Schmidt⁵  Subhash Rajpurohit⁵  Talia L Karasov⁶  Thomas JS Merritt⁷  Paula R Roy⁸  Brian P Lazzaro⁹  Kelly Dyer^1,10  Josefa González^1,11  Daniel K Fabian^1,12  Thomas Flatt^1,13  John E Pool^1,14  Iryna Kozeretska^1,15  Svitlana Serga^1,15 

[1] Department of Biology, Stanford University, Stanford, United States;Department of Biology, Stanford University, Stanford, United States;Department of Biology, University of Virginia, Charlottesville, United States;Department of Biology, Stanford University, Stanford, United States;Wellcome Sanger Institute, Hinxton, United Kingdom;Department of Biology, The Pennsylvania State University, University Park, United States;Department of Biology, University of Pennsylvania, Philadelphia, United States;Department of Biology, University of Utah, Salt Lake City, United States;Department of Chemistry & Biochemistry, Laurentian University, Sudbury, Canada;Department of Ecology and Evolutionary Biology, University of Kansas, Lawrence, United States;Department of Entomology, Cornell University, Ithaca, United States;Department of Genetics, University of Georgia, Athens, United States;Institute of Evolutionary Biology, CSIC- Universitat Pompeu Fabra, Barcelona, Spain;Institute of Population Genetics, Vetmeduni Vienna, Vienna, Austria;Centre for Pathogen Evolution, Department of Zoology, University of Cambridge, Cambridge, United Kingdom;Institute of Population Genetics, Vetmeduni Vienna, Vienna, Austria;Department of Biology, University of Fribourg, Fribourg, Switzerland;Laboratory of Genetics, University of Wisconsin-Madison, Madison, United States;Taras Shevchenko National University of Kyiv, Kyiv, Ukraine;National Antarctic Scientific Centre of Ukraine, Taras Shevchenko Blvd., Kyiv, Ukraine;

关键词: evolution;    seasonal adaptation;    selection;    population genetics;    genomics;    fluctuating selection;    D. melanogaster;   

DOI  :  10.7554/eLife.67577

来源: eLife Sciences Publications, Ltd

【 摘 要 】

To advance our understanding of adaptation to temporally varying selection pressures, we identified signatures of seasonal adaptation occurring in parallel among Drosophila melanogaster populations. Specifically, we estimated allele frequencies genome-wide from flies sampled early and late in the growing season from 20 widely dispersed populations. We identified parallel seasonal allele frequency shifts across North America and Europe, demonstrating that seasonal adaptation is a general phenomenon of temperate fly populations. Seasonally fluctuating polymorphisms are enriched in large chromosomal inversions, and we find a broad concordance between seasonal and spatial allele frequency change. The direction of allele frequency change at seasonally variable polymorphisms can be predicted by weather conditions in the weeks prior to sampling, linking the environment and the genomic response to selection. Our results suggest that fluctuating selection is an important evolutionary force affecting patterns of genetic variation in Drosophila.

【 授权许可】

CC BY