The Italian Version of the Test Your Memory (TYM-I): A Tool to Detect Mild Cognitive Impairment in the Clinical Setting

Frontiers in Psychology

Cristina Di Dio¹  Rosa Capozzo¹  Cinzia Musarò¹  Maria Rosaria Barulli¹  Giancarlo Logroscino²  Marco Piccininni³  Rosanna Tortelli⁴  Andrea Brugnolo⁵  Ugo Lucca⁶ 

[1] Department of Clinical Research in Neurology, Center for Neurodegenerative Diseases and the Aging Brain, University of Bari “Aldo Moro”, “Pia Fondazione Cardinale G. Panico”, Tricase, Italy;Department of Clinical Research in Neurology, Center for Neurodegenerative Diseases and the Aging Brain, University of Bari “Aldo Moro”, “Pia Fondazione Cardinale G. Panico”, Tricase, Italy;Department of Basic Medical Sciences, Neuroscience and Sense Organs, University of Bari “Aldo Moro”, Bari, Italy;Department of Clinical Research in Neurology, Center for Neurodegenerative Diseases and the Aging Brain, University of Bari “Aldo Moro”, “Pia Fondazione Cardinale G. Panico”, Tricase, Italy;Institute of Public Health, Charité – Universitätsmedizin Berlin, Berlin, Germany;Department of Clinical Research in Neurology, Center for Neurodegenerative Diseases and the Aging Brain, University of Bari “Aldo Moro”, “Pia Fondazione Cardinale G. Panico”, Tricase, Italy;UCL Huntington’s Disease Centre, UCL Queen Square Institute of Neurology, University College London, London, United Kingdom;Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, and Mother-Child health (DINOGMI), University of Genoa, Genova, Italy;Clinical Psychology Unit, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ospedale Policlinico San Martino, Genoa, Italy;Laboratory of Geriatric Neuropsychiatry, Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy;

关键词: cognitive screening test;    test your memory-Italian version;    TYM;    mild cognitive impairment;    dementia;   

DOI  :  10.3389/fpsyg.2020.614920

来源: Frontiers

【 摘 要 】

The Test Your Memory (TYM) is a brief self-administered, cognitive screening test, currently used in several settings. It requires minimal administrator supervision and the computation of the final test score takes approximately 2 min. We assessed the discrimination ability of the Italian version of the TYM (TYM-I) in detecting Mild Cognitive Impairment (MCI) in clinical setting. TYM-I was administered to 94 MCI patients and 134 healthy controls. The clinical diagnosis of MCI was considered as the gold standard. An extended formal neuropsychological test battery was used to define MCI subtypes. Receiver Operating Characteristic (ROC) analyses were conducted to find the optimal cut-off and measure discrimination ability of TYM-I in detecting MCI. TYM-I had a similar area under the curve (AUC = 0.85) point estimate as Mini Mental State Examination (MMSE) (AUC = 0.83). A TYM-I score lower or equal to 36 was found to be optimal cut off to detect MCI. The TYM-I showed the highest discrimination ability among individuals aged more than 70 and high educational level (AUC = 0.89). The amnestic MCI subtype patients, compared to non-amnestic MCI patients, had worse performance in recall, orientation and visuospatial abilities TYM-I subscores. The TYM-I is a valid screening test in detecting cognitive dysfunction, easily carried out in clinical practice. The TYM-I subscores may allow to identify amnestic and non-amnestic MCI subtypes.

【 授权许可】

CC BY