Nanomedicine: pharmacological perspectives

Nanotechnology Reviews

article

Santanu Bhattacharya¹  Khalid M. Alkharfy²  Rajiv Janardhanan³  Debabrata Mukhopadhyay¹ 

[1] Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine;College of Pharmacy and Biomarkers Research Program, King Saud University;Department of Radiology, Mayo Clinic;Department of Biomedical Engineering, Mayo Clinic

关键词: nanomedicine;    pharmacodynamics;    pharmacogenetics;    pharmacokinetics;    toxicity;   

DOI  :  10.1515/ntrev-2011-0010

学科分类：社会科学、人文和艺术（综合）

来源: De Gruyter

【 摘 要 】

Rapid developments in the field of nanotechnology are generating enormous interest in prospecting the potential of multifunctional therapeutic nanovectors in the field of personalized medicine. Although the nanomaterials are of same dimensions to many cellular machineries, their interaction with cells, tissues and organs of the body are not well understood. This in turn forms the rationale for a comprehensive study of these nanoplatforms in various disease models in terms of their toxicity, pharmacokinetics, pharmacodynamics, and pharmacogenetics. Such a study will significantly aid in our quest in translating its application from bench to bedside.

【 授权许可】

CC BY