Facile approach to the synthesis of substituted thieno[2,3-d]pyrimidin-4-ones

Heterocyclic communications

article

Anna Hovhannisyan¹  Lilit Aristakesyan¹  Gagik Melikyan¹ 

[1] Yerevan State University

关键词: amines;    cyclocondensation;    enamines;    Gewald’s reaction;    thieno[2;    3-d]pyrimidin-4-ones;   

DOI  :  10.1515/hc-2012-0095

学科分类：内科医学

来源: De Gruyter

【 摘 要 】

Condensation of Gewald’s thiophenes substituted with a dimethylaminomethyleneamino group at position 2 with primary amines yields 5/6-aryl-thieno[2,3- d ]pyrimidin-4-ones with variable substituents at the N3 position.

【 授权许可】

CC BY|CC BY-NC-ND