A fascinating decade for the synthesis of 1,2-azoles

Heterocyclic communications

article

Subhendu Chakroborty¹  Chittaranjan Bhanja²  Satyaban Jena² 

[1] Department of Chemistry, Ravenshaw University;Department of Chemistry, Utkal University

关键词: 1;    2-azoles;    isothiazoles;    isoxazoles;    pyrazoles;    synthesis;   

DOI  :  10.1515/hc-2013-0017

学科分类：内科医学

来源: De Gruyter

【 摘 要 】

1,2-Azoles comprising pyrazoles, isoxazoles, and isothiazoles have occupied a distinctive position in the design and synthesis of novel biologically active compounds that exert remarkable pharmaceutical activities as medicines and agrochemicals. As a consequence, there has been an increasing interest among synthetic organic/medicinal chemists in the development of methodologies for the rapid access to these heterocycles. In this review, we have summarized the most significant advances in the construction of functionalized pyrazoles, isoxazoles, and isothiazoles reported in the literature up to 2012.

【 授权许可】

CC BY|CC BY-NC-ND