Silphos as an efficient heterogeneous reagent for the synthesis of 2-azetidinones

Heterocyclic communications

article

Maaroof Zarei¹  Aliasghar Jarrahpour² 

[1] Department of Chemistry, College of Sciences, Hormozgan University;Department of Chemistry, College of Sciences, Shiraz University

关键词: 2-azetidinone;    β-lactam;    ketene;    Schiff base;    silphos;    Staudinger reaction;   

DOI  :  10.1515/hc-2014-0177

学科分类：内科医学

来源: De Gruyter

【 摘 要 】

This report provides a description of an efficient and simple procedure for the synthesis of 2-azetidinones via a one-pot reaction of imines and carboxylic acids in the presence of silicaphosphine at room temperature. The reagent is cheap and stable. The yields are good to excellent, and the reaction conditions are mild.

【 授权许可】

CC BY|CC BY-NC-ND