Regioselective 1,4-conjugate aza-Michael addition of dienones with benzotriazole

Heterocyclic communications

article

Zheng Li¹  Tianpeng Li¹  Rugang Fu¹  Jingya Yang¹ 

[1] College of Chemistry and Chemical Engineering, Northwest Normal University

关键词: aza-Michael addition;    benzotriazole;    dienone;    regioselectivity;    synthesis;   

DOI  :  10.1515/hc-2016-0182

学科分类：内科医学

来源: De Gruyter

【 摘 要 】

The regioselective 1,4-conjugate aza-Michael addition of dienones with benzotriazole catalyzed by potassium acetate is described. A series of 3-(benzotriazol-1-yl)-1,5-diarylpent-4-en-1-ones were efficiently synthesized under mild conditions. This protocol has advantages of transition-metal free catalyst, high yield and high regioselectivity.

【 授权许可】

CC BY|CC BY-NC-ND