Microwave-assisted synthesis of isoindolinones via Pd-mediated tandem coupling reactions

Heterocyclic communications

article

Eduardo Mendoza-Pérez¹  Alfredo Vázquez¹ 

[1] Universidad Nacional Autónoma de México, Ciudad Universitaria

关键词: heterocyclic compounds;    isoindolinones;    palladium tandem reactions;   

DOI  :  10.1515/hc-2018-0029

学科分类：内科医学

来源: De Gruyter

【 摘 要 】

Palladium (Pd) coupling reactions have become an indispensable tool in modern synthetic organic chemistry. A simple procedure to obtain isoindolinones 7 bearing a quaternary C-atom, featuring a Pd-mediated tandem process, is presented. Readily available iodoamidoacrylate 3 and boronic acids 6 are used as the starting materials.

【 授权许可】

CC BY|CC BY-NC-ND