Polymer-supported Pd(0) catalyst for copper- and ligand-free Sonogashira reactions in aqueous media

Green Processing and Synthesis

article

Wen-Bin Yi¹  Xin-Lei Shi¹  Chun Cai¹  Wei Zhang² 

[1] School of Chemical Engineering, Nanjing University of Science and Technology;Department of Chemistry, University of Massachusetts Boston

关键词: aqueous reaction;    ligand-free catalysis;    polymethyl methacrylate;    Sonogashira reaction;    supported palladium catalyst;   

DOI  :  10.1515/gps-2012-0002

来源: De Gruyter

【 摘 要 】

The treatment of commercially available polymethyl methacrylate (PMMA) microspheres with palladium (Pd)Cl 2 and formaldehyde, generated supported Pd(0)-PMMA with 0.79 (wt)% catalyst loading. The catalyst has been used for copper- and ligand-free Sonogashira reactions in aqueous media. It is highly reactive for the reactions of iodobenzenes with aryl acetylenes or alkyl acetylenes. The performance of the recovered catalyst had no significant difference in five cycles. The Pd leaching was detected at a very low level (2.1–9.8 ppm) for each cycle. PMMA-supported PdCl 2 , Pd(OAc) 2 , PdCO 3 , and PdCl 2 (MeCN) 2 have also been tested for Sonogashira reactions.

【 授权许可】

CC BY