Carbon coated magnetic nanoparticles as supports in microwave-assisted palladium catalyzed Suzuki-Miyaura couplings

Green Processing and Synthesis

article

Sebastian Wittmann¹  Jean-Pierre Majoral²  Robert N. Grass³  Wendelin J. Stark³  Oliver Reiser¹ 

[1] Institute of Organic Chemistry, University of Regensburg;CNRS Coordination Chemistry Laboratory;Institute of Chemical and Bioengineering, Department of Chemistry and Applied Biosciences

关键词: magnetic nanoparticles;    microwave irradiation;    palladium-N-heterocyclic carbene catalysts;    recyclable catalyst;    Suzuki-Miyaura coupling;   

DOI  :  10.1515/gps-2012-0036

来源: De Gruyter

【 摘 要 】

A palladium bis- N -heterocyclic carbene complex was immobilized on polystyrene modified, magnetic carbon coated iron nanoparticles and evaluated in Suzuki-Miyaura cross-coupling reactions under conventional and microwave heating. Under the latter conditions, both aryl bromides and aryl chlorides could be employed as substrates at low loading of catalyst (0.2 mol%), which could be readily recovered by an external magnet and reused in at least four cycles. As a possible deactivation pathway of the catalyst, the formation of palladium nanoparticles in the course of the reaction that became encapsulated in the polystyrene matrix of the support is suggested.

【 授权许可】

CC BY