Mono- and double carbonylation of iodobenzene in the presence of reusable supported palladium catalysts

Green Processing and Synthesis

article

Máté Papp¹  Béla Urbán¹  Eszter Drotár²  Rita Skoda-Földes¹ 

[1] Institute of Chemistry, Department of Organic Chemistry, University of Pannonia;Research Centre for Natural Sciences, Institute of Materials and Environmental Chemistry, Hungarian Academy of Sciences

关键词: carbonylation;    ionic liquid;    ketoamide;    palladium;    silica support;   

DOI  :  10.1515/gps-2014-0093

来源: De Gruyter

【 摘 要 】

Various silica-supported palladium catalysts were prepared and tested in the carbonylation of aryl iodides in the presence of aliphatic amines and aniline. In the former reaction, the main products are the α-ketoamides, whereas monocarbonylation is favoured with aniline. Small modification of the support, of the palladium precursor, or of the conditions of immobilisation were found to affect considerably the outcome of the reactions and recyclability of the catalysts. Under optimum conditions, the phosphine-free palladium catalysts can be reused six to ten times without considerable loss of activity. By the proper selection of the solvent, the leaching of palladium into the reaction mixtures can be reduced considerably.

【 授权许可】

CC BY