期刊论文详细信息
Green Processing and Synthesis | |
Microwave-assisted one-pot syntheses of 4-aminoquinazolines | |
article | |
Wenting Song1  Shunli He1  Zeli Yuan1  Guangqing Yu1  Di Wu1  Qing Wu1  Minqing Zhang1  Yongzheng Chen1  Qinghong Hu1  | |
[1] School of Pharmacy, Zunyi Medical University | |
关键词: 4-aminoquinazoline; methodology; microwave assisted; one-pot syntheses; | |
DOI : 10.1515/gps-2015-0121 | |
来源: De Gruyter | |
【 摘 要 】
A simple, environmentally friendly, one-pot method for the synthesis of 4-aminoquinazolines using microwave irradiation has been developed. Structures of derivatives 3 , 4 , and 5 were confirmed by single-crystal X-ray diffraction. The in vitro cytotoxicity of each compound was investigated using an MTT assay with A549 and HepG2 cell lines to calculate half-maximal inhibitory concentrations.
【 授权许可】
CC BY
【 预 览 】
Files | Size | Format | View |
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RO202107200001791ZK.pdf | 746KB | download |