Glucocorticoids Should Be Used With Caution in Patients With SARS-CoV-2

Frontiers in Medicine

Yan Chen¹  Yong Guo²  Yingchuan Li³ 

[1] Department of Clinical Pharmocology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China;Department of Critical Care Medicine, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China;Department of Critical Care Medicine, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China;Department of Critical Care Medicine, Shanghai Public Health Clinical Center, Fudan University, Shanghai, China;

关键词: glucocorticoid;    COVID-19;    SARS-CoV-2;    pneumonia;    inflammation;   

DOI  :  10.3389/fmed.2021.564943

来源: Frontiers

【 摘 要 】

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a global pandemic, and the use of glucocorticoids in clinical practice is controversial. Our clinical experiences with glucocorticoid treatment suggested that, while use was effective in some cases, in other cases, glucocorticoid were ineffective and even resulted in immunosuppression that could lead to deterioration. Therefore, glucocorticoids should be used with caution in patients with SARS-CoV-2.

【 授权许可】

CC BY